Dynamics of neurocognitive indicators against the background of neuroprotective therapy of vertebrobasilar insufficiency with cerebral venous discirculation symptoms

The aim of the study was to assess effect Cytoflavin on severity neurocognitive parameters in patients with chronic cerebral ischemia, as well vertebrobasilar insufficiency symptoms venous circulation. involved 60 who were divided into two groups. prescribed treatment group: once per day morning, slow intravenous drip 10.0 ml 200 0.9% sodium chloride solution, duration infusion averaged 40–60 minutes for a course 10 days transition tablet form — 2 tablets twice 30 against background standard basic therapy (acetylsalicylic acid and antihypertensive drugs). Patients comparison group received only therapy. rating scales headache (visual analogue scale) asthenia (asthenic state used neurological status addition clinical labo ratory examination. It revealed that main manifestations discirculation are headaches (48 (80%) patients) dizziness (53 (88.3%) patients). incidence increased progression example, at stage I occurred 57% cases, II 78%, III 100%. When conducting dynamics VAS scale, decrease intensity by 1.7 times (5.68±0.62 3.23±0.56 points, p[1]0.5) noted Cytoflavin, while slight pain group. In addition, inclusion drug regimens this pathology showed significant frequency complaints, including specific «venous» cephalgic syndrome, asthenic autonomic disorders, which had positive patients’ quality life. results obtained make it possible recommend dysfunction.